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Genetic Engineering Offers Hope for SLE Cure

Systemic Lupus Erythematosus (SLE) is an autoimmune disease where immune system doesn’t recognise its own organs and attacks to destroy it. More than one million patients are suffering from this disease per year where prevalently females suffer. Present medical science has no remedy to cure it. It manages the symptoms with immuno-suppressive drugs and steroids. It reduces the flaring of organ inflammation and subsides the symptoms, but not curing it. Patient’s life become miserable, can survive for years together with miseries or sometimes, symptoms itself are life threatening. Baruah Applied Human Genetic Engineering helps to cure SLE by modifying immune system, so that it de-recognises its own organs as foreign organs by destroying diseased microRNAs responsible for SLE, so that correct protein will be synthesized and disease process will be reversed.
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HIV/AIDS and it’s cure

Human immunodeficiency virus (HIV) targets immune system of the host and destroy it. This leads the host susceptible to opportunistic infection. It’s life cycle is 1.5days from its entry into cell till releasing infecting new cells. HIV1 is more infective, non- specific for RNA,can mutate faster, leads to AIDs. On other hand HIV 2 is specific for messenger RNA and less pathogenic. Viral RNA cannot transcribe DNA correctly, which brings number of mutations in its genomic structure.This is the hurdle where scientists are unable to produce exact medication against HIV. Virus get Integrated with host DNA and become provirus, so that during investigation, it shows absence of virus in blood stream.Anti-retroviral treatment manages CD4 levels of the host, thereby, managing the symptoms, but not curing it. Baruah applied human genetic engineering targets the virus with Baruah siRNA and destroys it to cure the disease permanently.
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Revolutionizing Cancer Treatment

Cancer- it is a disease where normal cells become abnormal, starts multiplying, growing enormously and become parasitic on normal cells.They draw complete nutrition from normal cells, making normal cells weaker.

Different organs of the body can be affected with this disease and can spread to other susceptible organs. Cadherin, a protein which keeps cells together. But in cancer, this protein is defunct, cannot be produced, that makes Cancer cells to spread all over the body and spread of cancer take place. This process is called metastasis.

Heredity, chemical/radiation hazards, tobacco/ alcohol consumption/ diet can cause genetic mutations which can lead to cancer.

Chemotherapy, radiation therapy immunotherapy are available treatments in medical science without much successful results. These treatments are not localised to destroy cancer cells, but it destroys normal cells as well, making patient day by day weaker.

Dr. Baruah applied human Genetic engineering targets only cancer cell, correct the required mutation, cures the cancer without destroying normal cells. It cuts off blood supply to cancer cells depriving from nutrition, up- regulating cadherin synthesis stopping further spread of cancer.

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Revolutionizing Leukemia Treatment

Leukemia- Bone marrow is the manufacturing house of blood cells, that is RBC, WBC, Platelet etc. When it becomes defunct, it starts producing abnormal blood cells leaving behind scanty mature cells and enormous premature cells which can not function as mature cells.That’s why RBC can not carry out proper oxygenation, lack of WBC cause body susceptible to opportunistic infection, low platelets impair clotting mechanism.

Depending on progression and involvement of different types of blood cells, leukemia is categorised into four types – viz. acute lymphoblastic ( immature lymphocytes), chronic lymphocytic (mature lymphocytes), acute myeloid ( immature myeloid cells incl.RBC, platelet, some types of WBC), chronic myeloid (mature myeloid cells.) Genetic mutation due to chemicals, radiation, heredity can cause this disorder. Blood tests, bone marrow biopsy help to diagnose this disorder. Treatment available- chemotherapy, radiation, immunotherapy, stem cell therapy are presently available treatment in medical science.

Dr.Baruah has developed treatment with Baruah applied human Genetic engineering where his molecules Target the disease genes, either it destroys or repairs the damaged genes, produces normal bone marrow, this helps the patient to recover faster without destroying normal cells.

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Baruah Mechanical and Biological Heart Valves

In the realm of cardiac health, Dr. Dhani Ram Baruah has emerged as a beacon of innovation with its groundbreaking biological heart solutions. From state-of-the-art heart valves to a remarkable permanent implantable biological heart, Baruah’s commitment to enhancing the quality of life for patients is truly inspiring.

Baruah Biological Heart Valves:

Baruah’s biological heart valves are crafted from bovine treated pericardium, offering unparalleled durability. The stented version boasts an impressive longevity of 52.4 patient years, while the stentless counterpart pushes the envelope further, with an astonishing 92.8 patient years of reliability. These valves closely mimic the performance of native heart valves, ensuring patients can enjoy a healthier and more fulfilling life.

Baruah Heart 21:

Perhaps the most groundbreaking achievement in the world of cardiac care is the Baruah Heart 21. This remarkable innovation is a completely permanent implantable biological heart, powered by an electric motor. Imagine a life where the constraints of heart health are a thing of the past, thanks to Baruah’s vision of a brighter, healthier future.

In summary, Baruah’s dedication to pioneering solutions in cardiac health, from their longevity-enhancing heart valves to the awe-inspiring Baruah Heart 21, is poised to transform lives and redefine the landscape of cardiology. With durability and innovation at its core, Baruah is a name that promises hope and a new lease on life for countless individuals seeking a healthier heart.

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Why Carnivorous have more Destructive Mutation than Herbivorous

In realities, my genomic studies have suggested that pure carnivorous animals are getting extinct than herbivorous and omnivorous, such as lions , tigers, foxes are purely carnivorous, Pigs, Dogs, Non Human primates are omnivorous, Elephants , Deers, Wild buffaloes are purely Herbivorous.

MiRNA of purely herbivorous animals are not having Destructive mutation than purely carnivorous Animals. Their survival incidence and longevity is very small and they are prone to have incurable diseases. Their mental status is more dangerous and destructive, which becomes a greater stimulus for mutation of miRNA which ultimately expressing in form of incurable disease leading to premature death. This is one of the major factor for extinction in comparison.

In case of non- human primates, baboon and chimpanzee is the cause of extinction is the incurable disease and stopping the further production due to instability of miRNA. Instability of miRNA is caused by their change of mental status which acts as stimulus to make miRNA unstable and restricting the translation process for synthesizing beneficial protein. Superiority complex of non human primates as stimulus to trigger the signal transduction and ultimately stimulating the instability of miRNA for detrimental protein synthesis at the stage of translation, which becomes the barrier of health production and slow extinction is inevitable.

In Human , rapid extinction has been seen in case of Eskimoes, Australian aborigines, Red Indians of USA & Indians in Cananda. The government of these countries are alerted and trying to conserve these extinct species. But unfortunately, they are finding it to be difficult. The extinction is due to their ill or un-natural habits of living, which becomes the greater stimulus for causing instability to cause the signal transduction and they die of incurable disease and slows down the production. I suggest that will not be too long to see that those human species will be disappeared.

I find through my experience of total human genomic mapping and observing the instability of miRNA of many communities of India.

My studies on total human genetic mapping have suggest instability and stability of miRNA resulting the detrimental or beneficial effect are based on environmental and individual stimulus. It doesnot matter how big or small the stimulus, the effect is always indirectly proportional to it

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A Potential Cure for Coronary Artery Disease Without Surgery

Coronary artery disease is a progressive generalised disease involving entire arterial tree of the individual. Means, though it is labelled as coronary artery disease, it is not only blockages of coronary arteries, entire arterial tree is getting blocked with blockages with blood cells, lipids and other debris. Coronary arteries supply blood to myocardium. Any obstruction to coronary arteries deprive blood to heart cells, lacking nutrition & oxygen supply,causing heart attack & death depending on severity of the attack.Many factors such as sex, age, hypertension, heredity,diabetes, sedentary life style, obesity, stress, fatty diet, smoking & alcohol drinking are major risk factors. Coronary artery bypass surgery or angioplasty are palliative surgical procedures which give temporary relief to CAD patients, where 100%recurrence is inevitable.In addition to this, entire arterial tree give low perfusion to end organs due to high viscosity of blood in CAD patients.Using diseased saphenous vein, mammary arteries as conduits to bypass the diseased arteries in coronary artery bypass surgery is useless surgical procedure as patient has to come for re-do surgery.Baruah applied human Genetic engineering targets diseased microRNA responsible for CAD and cure the disease without bypass surgery.
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Advantages of Baruah Applied Human Genetic Engineering over bypass surgery

Coronary artery Bypass SurgeryBaruah Applied Human Genetic Engineering
1. Temporary & palliative surgical procedure.1. Permanent cure with bio- molecules in unaltered from isolated from edible medicinal plants.
2. Diseased arteries or veins from patient’s own body are used as a conduit.2. M-RNA expressed diseased multi- genes responsible for coronary artery disease are corrected by engineering miRNA.
3. Disease remains in situ hence progressiveness of the disease is very aggressive.3. Root cause of the disease is removed hence no recurrence.
4. Patient lives with uncertain future.4. Patient lives healthy life.
5. Results in premature death.5. Eliminates premature death.
6. Side Effects & complications are surmountable.6. No side effects & complications.
7. Complete surgical procedure with investigations such as tread mill test, coronary angiography is costly affair.7. Baruah new invasive technique for calculating coronary artery blockages using Colour Doppler studies is cheaper.
8. Patient has to live long with handful of medicines with lots of side effects.8. No life long medication is required.
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Role of Baruah Nuclear Head Missile Baruah siRNA

The biological events in entire race of human primates are really a mystery. Any detrimental biological event must be handled biologically as synthetic molecules till now not been developed without any side effect . The simple example I can site in this respect. We are biological species, our system has not been developed and grown since we are born synthetically using synthetic molecules. Our system has been developed with biological molecules that we are getting from food at molecular level using as fuel and on the basis of this concept, I have identified and isolated the molecules made by the nature in form of edible medicinal plant, which does work satisfactory & beautifully to combat the irregularities in genetic machineries caused by mistaken stimulus during the course of human life. I would like to declare that this theory can never be erased forever . Baruah Biological molecule must be used at the events mentioned above and must not be neglected particularly 3rd and 4th events as one should not think that mutation is silent, does not mean that it will remain silent forever. The silence is always circumstantial.

In case of germ line mutation which transfer the disease from parents to offspring, can be dependable on the stimulus. Even the germ line mutation can remain silent and child will not suffer from the disease clinically. The genetic morphology can change the functionality according to the environment. Therefore , it explains clearly, although the same mistaken genes are available in all the children of the family, some will suffer and some will not. That entirely depends on subsequent mistaken stimulus. In this connection, I would like to site the example- Some mistaken genes of that particular child of that family is sensitive to tobacco or its preparation, which acts as the stimulus to trigger the signal transduction which may express in form of heart disease or cancer. However, his brother or sister having same mistaken genes taking tobacco or its preparation will not cause the further mutation to synthesize wrong protein and as a result, this process will not be expressed in disease form